Factor XII Deficiency in dogs

Species: Dog
Condition: Factor XII Deficiency
Organ System: Nervous/sensory

Factor XII is one of the many proteins essential in complex process of blood clotting. In its absence that process might be impaired. But, in comparison to deficiencies of other similar factors, this one causes only mild symptoms. The animal is therefore never in danger of life threatening blood loss. Affected dogs can have small amounts of blood in their stool as a result of mild bleeding after a minor, insignificant injury of the digestive system organs. They are also somewhat more prone to bleeding after cuts and bruising, but overall health is actually never impaired. Such dogs are perfectly capable of leading a normal and healthy life.

Breeds exposed to Factor XII Deficiency – Research Reference
Alsatian Cross – University of Sydney (LIDA Dog Disease Database)
Airedale Terrier Cross – University of Sydney (LIDA Dog Disease Database)
Cairn Terrier Cross – University of Sydney (LIDA Dog Disease Database)
German Wire Haired Pointer Cross – University of Sydney (LIDA Dog Disease Database)
Lhasa Apso Cross – (Mauser et al. 1996)
“Maltese Cross – (Brodey & Kelly 1968
Old English Sheepdog Cross – University of Sydney (LIDA Dog Disease Database)
Alaskan Malamute Cross – University of Sydney (LIDA Dog Disease Database)
American Cocker Spaniel Cross – University of Sydney (LIDA Dog Disease Database)
Pyrenean Mountain Dog Cross – University of Sydney (LIDA Dog Disease Database)
“Rottweiler Cross – (Brodey & Kelly 1968
French Bulldog Cross – University of Sydney (LIDA Dog Disease Database)
Black and Tan Coonhound Cross – University of Sydney (LIDA Dog Disease Database) & (Dodds 2005)
St Bernard Cross – (Dodds 2005) & University of Sydney (LIDA Dog Disease Database)
Scottish Terrier Cross – University of Sydney (LIDA Dog Disease Database)
“Shih Tzu Cross – (Brodey & Kelly 1968
German Shepherd Cross – University of Sydney (LIDA Dog Disease Database)
Shetland Sheepdog Cross – University of Sydney (LIDA Dog Disease Database)
Cairn Terrier – University of Sydney (LIDA Dog Disease Database)
French Bulldog – University of Sydney (LIDA Dog Disease Database)
German Shepherd – University of Sydney (LIDA Dog Disease Database)
Old English Sheepdog – University of Sydney (LIDA Dog Disease Database)
Pyrenean Mountain Dog – University of Sydney (LIDA Dog Disease Database)
Scottish Terrier – University of Sydney (LIDA Dog Disease Database)
Shetland Sheepdog – University of Sydney (LIDA Dog Disease Database)
St Bernard – University of Sydney (LIDA Dog Disease Database) & (Dodds 2005)
Black and Tan Coonhound – University of Sydney (LIDA Dog Disease Database) & (Dodds 2005)
Airedale Terrier – University of Sydney (LIDA Dog Disease Database)
Alaskan Malamute – University of Sydney (LIDA Dog Disease Database)
American Cocker Spaniel – University of Sydney (LIDA Dog Disease Database)
Bichon Frise – University of Sydney (LIDA Dog Disease Database)
English Springer Spaniel – University of Sydney (LIDA Dog Disease Database)
German Wire Haired Pointer – University of Sydney (LIDA Dog Disease Database)
Labradoodle – University of Sydney (LIDA Dog Disease Database)
Alsatian – University of Sydney (LIDA Dog Disease Database)
Springer Spaniel – University of Sydney (LIDA Dog Disease Database)
Labrador Cross – University of Sydney (LIDA Dog Disease Database)
English Springer Spaniel Cross – University of Sydney (LIDA Dog Disease Database)
Labrador Retriever Cross – University of Sydney (LIDA Dog Disease Database)
Bichon Frise Cross – University of Sydney (LIDA Dog Disease Database)
Labrador – University of Sydney (LIDA Dog Disease Database)
Labrador Retriever – University of Sydney (LIDA Dog Disease Database)
Springer Spaniel Cross – University of Sydney (LIDA Dog Disease Database)
“Rottweiler – (Brodey & Kelly 1968
“Maltese – (Brodey & Kelly 1968
“Shih Tzu – (Brodey & Kelly 1968
Lhasa Apso – (Mauser et al. 1996)
Labradoodle Cross – University of Sydney (LIDA Dog Disease Database)

Disease Author
Dr Merliza Cabriles, Professor of Veterinary Medicine

To learn more about Factor XII Deficiency or any other condition we invite you to search this website. Even better, pick up the phone and call your vet. Your vet knows your pet better than anyone else and is a fountain of information.